Egg Yolk Immunoglobulins Used as Additives in Meat Quality
Keywords:
Egg yolk immunoglobulins, meet qualityAbstract
The quality of food and feed is more and more in the first place of research, being tightly related to the health state of humans and animals. Due to these features, antibiotics used in animals are no longer agreed to be used, and natural supplements are encouraged to be used to increase the meat's nutritional quality. One of the natural immunoglobulins used as a replacement for antibiotics is egg yolk immunoglobulin Y (IgY), which is added in diet supplementation for feeding animals. The combination of probiotics and other substances with an immunological role, especially some natural immunoglobulins - such as IgY, has multiple advantages. Thus, it can be increased meat production, improve the immunological status of animals which decreases the stress effects, improve infection resistance, increase the quality of carcasses - which implicitly also leads to economic growth, and also obtaining animal products without the addition of antibiotics or growth stimulants, or even obtaining organic products. There are several cost-effective methods to extract natural immunoglobulin IgY from egg yolk: using dextran blue, polyethylene glycol, chloroform, and cryo-ethanol treatment followed by precipitation with ammonium sulfate. In this paper, we will present some features regarding the methods of extracting IgY immunoglobulins from the egg yolk, the way of using these immunoglobulins in animal breeding and improvement technologies, as well as the biotechnological advantages that derive from the use of this natural product.
References
Yakhkeshi, S., Wu, R., Chelliappan, B., Zhang X., Trends in industrialization and commercialization of IgY technology, Front. Immunol., 2022, 13, 991931.
Rehan, I.F., Youssef, M., Abdel-Rahman, M.A.M., Fahmy, S.G., Ahmed, E., Ahmed, A.S., The Impact of Probiotics and Egg Yolk IgY on Behavior and Blood Parameters in a Broiler Immune Stress Model. Frontiers in Veterinary Science, 2020 , 7.
Chalghoumi, R., Beckers, Y., Portetelle, D., Théwis, T., Hen egg yolk antibodies (IgY), production and use for passive immunization against bacterial enteric infections in chicken: a review., BASE Biotechnologie, Agronomie, Société et Environnement/Biotechnology, Agronomy, Society and Environment, 2009, 2, 13.
Bundurus, I.A., Balta, I., Stef, L., Ahmadi, M., Pet, I., McCleery, D., Corcionivoschi, N., Overview of Virulence and Antibiotic Resistance in Campylobacter spp. Livestock Isolates, Antibiotics-Basel, 2023, 12(2), Article nr: 402.
Diraviyam, T., Zhao, B., Wang, Y., Schade, R., Michael, A., & Zhang, X. Effect of Chicken Egg Yolk Antibodies (IgY) against Diarrhea in Domesticated Animals: A Systematic Review and Meta-Analysis. Plos One, 2014, 9(5), e97716.
Chalghoumi, R., Beckers, Y., Portetelle, D., Théwis, A.. Hen egg yolk antibodies (IgY), production and use for passive immunization against bacterial enteric infections in chicken: a review, 2009, 13, 2.
Hussein, M. A., Rehan, I. F., Rehan, A. F., Eleiwa, N. Z., Abdel-Rahman, M. A. M., Fahmy, S. G., Ahmed, A. S., Youssef, M., Diab, H. M., Batiha, G. E., Alrashood, S. T., Khan, H. A., Shanab, O., Ahmed, E., Hassan, H., Elnagar, A., Elkelish, A., Hesham, A. E., & Maky, M. A. Egg Yolk IgY: A Novel Trend of Feed Additives to Limit Drugs and to Improve Poultry Meat Quality. Frontiers in veterinary science. 2020, 7, 350.
Butucel, E., Balta, I., Ahmadi, M., Dumitrescu, G., Morariu, F., Pet, I., Stef,L., Corcionivoschi, N., Biocides as Biomedicines against Foodborne Pathogenic Bacteria, Biomedicines, 2022, 10, 2, Article no. 379.
Stefaniak, T., Rząsa, A., Jawor, P., Zyzak, A., Niemczuk, W., Kuczaj, M., Popławski, M., Borkowski, J., Field application of egg yolk immunoglobulin as the feed additive in prophylaxis of diseases in weaned piglets. Med Weter, 2014, 70, 9, 553–7.
Hussein, M.A., Rehan, I.F., Rehan, A.F., Eleiwa, N.Z., Abdel-Rahman, M.A.M., Fahmy, S.G., Ahmed, A.S., Youssef, M., Diab, H.M., Batiha, G.E., Alrashood, S.T., Khan, H.A., Shanab, O., Ahmed, E., Hassan, H., Elnagar, A., Elkelish, A., Hesham, A.E., Maky, M.A. Egg Yolk IgY: A Novel Trend of Feed Additives to Limit Drugs and to Improve Poultry Meat Quality. Frontiers in veterinary science, 2020, 7, 350.
Xiaoyu Li, Lili Wang, Yuhong Zhen, Shuying Li and Yongping Xu. Chicken egg yolk antibodies (IgY) as non-antibiotic production enhancers for use in swine production: a review. Journal of Animal Science and Biotechnology, 2015, 6, 1–10.
Diraviyam, T., Senthil, V.A., Ricardo, S.V.P., Zhang, X., Saravanan, S., Umamaheswari, K., Chiken egg yolk antibody (IgY) as diagnostics and therapeutics in parasitic infections – A review, Int. J. Biol. Macromol., 2019, 136, 755-763.
Wang, Z., Li, J., Li, J., Li, Y., Wang, L., Wang, Q., Fang, L., Ding, X., Huang, P., Yin, J., Yin, Y., Yang, H., Protective effect of chicken egg yolk immunoglobulins (IgY) against enterotoxigenic Escherichia coli K88 adhesion in weaned piglets. BMC Veterinary Research, 2019, 15(1), 234.
Tong, C., Geng, F., He, Z., Cai, Z., Ma, M., A simple method for isolating chicken egg yolk immunoglobulin using effective delipidation solution and ammonium sulfate. Poultry Science, 2015, 94(1), 104–10.
da Silva, G.B., da Faria, L.S., Lopes, C.A., Nunes, D.S., Ribeiro, V.S., de Sousa, J.E.N., Paiva, G.C.M., Goncalves-Pires, M.R.F., Borges, I.P., Santos, M.M., Avila, V.M.R., Junior, A.F., Costa-Cruz, J.M, Egg yolk immunoglobulin Y as a promising tool to detect immune complexes in neurocysticercosis serum samples, Trans. R. Soc. Trop. Med. Hyg., 2020, 114(8), 585–592.
Shikun, G., Yanli, Y., Brindha, C., Antonysamy, M., Fagang, Z., Xiaoying, Z., Evaluation of Different IgY Preparation Methods and Storage Stability as Potential Animal Feed Supplement. Pakistan Journal of Zoology, 2020, 52(6), 2027-2426.
Yegani, M., Korver, D.R., Application of egg yolk antibodies as replacement for antibiotics in poultry. World’s Poultry Science J., 2010, 66, 27–38.
Bizhanov, G., Vyshniauskis, G., A comparison of three methods for extracting IgY from the egg yolk of hens immunized with Sendai virus. Veterinary research communications, 2000, 24(2), 103–113.
Pauly, D., Chacana, P.A., Calzado, E.G., Brembs, B., Schade, R., IgY technology: extraction of chicken antibodies from egg yolk by polyethylene glycol (PEG) precipitation. Journal of visualized experiments, JoVE, 2011, 51, 3084.
Amro, W.A., Al-Qaisi, W., Al-Razem, F., Production and purification of IgY antibodies from chicken egg yolk. Journal, genetic engineering & biotechnology, 2018, 16(1), 99–103.
