Chemical Composition and Antimicrobial Activity of Royal Jelly - Review
Keywords:
antimicrobial activity, chemical composition, royal jellyAbstract
The present paper presents the literature data regarding the chemical composition and antimicrobial activity of Royal Jelly. Royal Jelly is a secretion from the hypofaringeal glands of worker bees which serves as a food for queen bee and to the growing up larvae. Having biological properties already proven, Royal Jelly has considerable commercial appeal and is today used in many sectors (pharmaceutical, food industries and cosmetic products). The physicochemical composition of pure royal jelly are analyzed by determining moisture, ash, lipids, proteins,vitamins, aminoacids, carbohydrates, 10-HDA; RJ is the key substance in the antimicrobial function of the system Apis mellifera. The intact Royal Jelly exhibited the highest antibacterial activity.
References
Vichai, W., Treetip, R., Seasonal Variation of Chemical Composition of Royal Jelly Produced in Thailand, Thammasat Int. J. Sc. Tech, 2002, 7, 23
Sabatini., A. G., Marcazzan, L. G., Caboni., M. F., Bogdanov, S, Bicudo de Almeida-Muradian, L., Quality and Standardisation of Royal Jelly,Journal of ApiProduct and ApiMedical Science, 2009, 16-21
Lercker, G., La gelatina reale: composizione, autenticita ed adulterazione, In Atti del Convegno „Strategie per la valorizzazione dei prodotti dell' alveare”. Universitá degli Studi del Molise; Campobasso; 2003, 67-81
Piana, M. L, Paola, B., Livia P. O., Sara, P., Pollen Analysis of Royal Jelly: Contribution to Analytical Methods and Characterization, Via L. Rech, 36, 00156
Andreas, S., Peter, S., Antonius, K., Eberhard, B., Trace and mineral elements in royal jelly and homeostatic effects, Journal of Trace Elements in Medicine and Biology, 2005, 183-189
Eshraghi, S., Seifollahi, F., Antibacterial Effects of Royal Jelly on Different Strains of Bacteria, Iranian J. Publ. Health, 2003, 32, 1, 25-30
Vittek, J., Effect of Royal Jelly on serum lipids in experimental animals and humans with atherosclerosis, 1995, Experientia, 51, 927 -35
Messia, M. C., Caboni, M. F., Marconi E., Storage stability assessment of freeze dried RJ by furosine determination, Journal of Agriculture and Food Chemistry 53, 2005, 4440-4443
Ferioli, F., Marcazzan, G. L, Caboni, M. F., Determination of (E) – 10 hydroxy-2-decenoic acid content in pure royal jelly: a comparison between a new CZE method and HPLC. Journal of separation Science, 2007, 30, 1061-1069
Garcia-Amoedo, L. H., Almeida-Muradian, L. B., Physicochemical composition of pure and adulterated royal jelly, Quimica Nova, 2007, 30(2), 257-259
Lercker, G; Caboni, M, F; Vecchi, M, A; Sabatini, A. G; Nanetti, A., Caratterizzazione dei principali constituent della gelatin reale, Apicoltura, 1993, 8, 27-37
Boselli, E; Caboni, M. F., Sabatini, A, G., Marcazzan, G, L., Lercker, G., Determination and changes of free amino acids in royal jelly during storage, Apidologie, 2003, 34, 1-7
Sesta, G., Determination of sugars in royal jelly by HPLC, Apidologie, 2006, 37, 84-90
Bloodworth, B, C., Harn, C, S., Hock, C. T., Boon Y. O., Liquid chromatographic determination of trans-10-hydroxy-2-decenoic acid content of commercial products containing royal jelly, J.AOAC Int., 1995, 78 (4), 1019-1023
Koshio, S., Almeida, Muradian, L. B., - Aplicação da CLAE para determinação do ácido 10-hidróxi-2-decenóico (10-HDA) em geléia real pura e adicionada a mel brasileiro. Quim. Nova, São Paulo, 2003, 26, 5, 670-673
Pamplona, L. C., Azedo, R, A. B., Oliveira, K; Garcia-Amoedo, L, H; Almeida-Muradian, L. B., Physicochemical analyses indicated to the quality control of royal jelly with honey. Ciencia y tecnología de alimentos, 2004, 24, 608-612
Benfenati, L., Sabatini, A. G., Nanetti, A., Composizione in sali minerali della gelatina reale., Apicoltura, 1986, 2, 129-143
Bonvehi, J., Azucares, acidez y pH de la jalea real. Anales de Bromatologia, 1992, 44(1), 65-69
Ricciardelli D'albore, G., Analisi microscopica del miele e della gelatina reale: possibilità di applicazione e limiti. Atti della Accademia gioenia di Scienze Naturali in Catania, 1986, 19: 45-60.
Marconi, E., Carboni, M. F., Messia, M. C., Panfili, G., Furosine: a suitable marker for assessing the freshness of Royal Jelly, Journal of Agricultural and Food Chemisty, 2002, 50, 297 – 300
Messia, M. C., Caboni, M. F., Marconi, E., Valutazione della freschezza della gelatin reale. In Atti del Convegno “Strategie per la valorizzazione dei prodotti dell'alveare”, Universitá degli Studi del Molise; Campobasso; 2003, 83-92
Šimuth, J., Some properties of the main protein honeybee (Apis Mellifera L.) royal jelly, Apidologie, 2001, 32, 69-80
Bachanova, K., Klaudiny, J., Kopermichy, J., Šimuth, J., Identification of honeybee peptide active against Paenybacillus larvae through bacterial growth-inhibition assay on polyacrylamide gel, Apidologie, 2002, 33, 259-269
http://membres.lycos.fr/ecrausaz/Jalea-real.html
Antinelli, J. F., Davico, R., Rognone, C., Faucon, J. P., Cuvelier, L. L., Application of Solid/Liquid Extraction for the Gravimetric Determination of Lipids in Royal Jelly, Journal of Agricultural and Food Chemistry, 2002, 50, 2227 – 2230
Bullet, P., Hetru, C., Dimarcq, J. L, Hoffman, D., Antimicrobial peptides in insects: structures and function. Dev Comp Immunol., 1999; 23, 329-44
Fujiwara, S., Imai$, J., Fujiwara, M., Yaeshima, T., Kawashima, T., and Kobayashit, K., A Potent Antibacterial Protein in Royal Jelly purification and determination of the primary structure of royalisin, the Journal of Biological Chemistry, 1990, 265(19), 11333-11337
Bíliková, K., Hanes, J., Nordhoff, E., Saenger, W., Klaudiny, J., Šimúth, J., Apisimin, a new serine valin-rich peptide from honeybee (Apis mellifera L.) royal jelly: purification and molecular characterization. FEBS Letters, 2002, 528, 125-129
Fontana, R., Maria, A., Mendesb, B., Monson de Souza, K., Konno ,L´ılian Mari M. César, Osmar Malaspina, Palma, M. S., Jelleines: a family of antimicrobial peptides from the Royal Jelly of honeybees (Apis mellifera), Peptides, 2004, 25, 919–928
Juraj Majta´n , Elena K., Katarına., Bı´likova´ , J. Simuth, The immunostimulatory effect of the recombinant apalbumin1–major honeybee royal jelly protein–on TNFa release, International Immunopharmacology, 2006, 269– 278
Zhou, Jinhui., Xue, X., Li, Yi., Zhang, Jinzhen., Zhao, Jing, Optimized determination method for trans-10-hydroxy-2-decenoic acid content in royal jelly by high-performance liquid chromatography with an internal standard, Journal of AOAC International , 2007, 90, 1, 244 – 249