MALATHION INDUCED HISTOLOGICAL MODIFICATIONS IN GILLS AND KIDNEY OF CARASSIUS AURATUS GIBELIO
Keywords:
Carassius auratus gibelio, malathion, histological modificationsAbstract
Malathion is an organophosphorous insecticide, used in agriculture and a possible
source of environmental poisoning. During malathion metabolization, mitochondria
generates reactive oxygen species, responsible for significant structural changes. In
this study, gills and kidney histological changes in Carassius auratus gibelio
exposed to 0.05 mg/l malathion were investigated. In kidney, the effects were
dramatic. The 24 -72 hours exposure to malathion induced cytoplasm vacuolization
and changes in cell and nuclear volumes. In addition, necrotic renal tubules
appeared, nuclear malformations of epithelial cells, anisokary, nuclei pycnosis and
nuclei hypertrophy, were noticed. Epithelial ruptures, secondary lamellae fusion and
hyperplasia of branchial epithelium, vascular congestion were the main changes
noticed soon after pollutant exposure. We suggest that structural changes in gill and
kidney could be used as good response to aquatic pollution with organophosphorous
insecticides.
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