PATHOLOGICAL TISSUE LESIONS INDUCED BY CHRONIC MERCURY INTOXICATION IN SILVER CRUCIAN CARP CARASSIUS AURATUS GIBELIO
Keywords:
fish, chronic mercury intoxication, histopathological changeAbstract
The purpose of this work was to describe the histopathological effects of chronic
inorganic mercury intoxication on liver, gills, kidneys, small intestine and skin in
silver crucian carp Carassius auratus gibelio. 20 immature 1+-year-old crucian
carp were obtained from a private fishfarm and acclimatized to laboratory
conditions. After a 3 weeks exposure to a sublethal mercury concentration (0.25 ppm
from a HgCl2 stock solution), liver, gills, kidney, small intestine and skin were
sampled and processed for histological examination.The main effects observed:
numerous interstitial leukocytar infiltrates, followed by glomerulonephritis and
tubulonephritis there are at the renal level; fibrosation of peri- and interlobular
conjunctive tissue, including ectasiated blood vessel and numerous limphocytar
infiltrates enlarged both in perilobular and intralobular conjunctive tissue at the
liver level; an disorganization process of gill lamellae by superficial layer
alteration, at the gill level; cells of skin epiderma exhibit hiperplazic hypertrophy,
epithelial desquamation, intraepithelial edema and citoplasmatic vacuolization;
light epithelial distrophic processes and an abundant leukocytar infiltrate both in
vilositaire chorion and basal chorion at the small intestine level.
References
Banerjee, S., Bhattacharya, S., (1997) - Histopathological changes
induced by chronic nonlethal levels of elsan, mercury and ammonia in the small
intestine of Channa punctatus (Bloch). Ecotoxicol. Environ. Saf. 31, 62–68.
C.A. Oliveira Ribeiro, L. Belger, E. Pelletier, C. Rouleauc (2002) -
Histopathological evidence of inorganic mercury and methyl mercury toxicity in
the arctic charr (Salvelinus alpinus), Environmental Research, 90, 217–225
Gupta Neeraj, Dua Anish (2002) - Mercury induced architectural
alterations in the gill surface of a fresh water fish, Channa punctatus. J Environ
Bio, 23(4) 383-386 [14 Ref].
Khan M.S., Khan S.A., Chaudhary Z.I, Khan M.N., Aslam A., Ashraf
K., Ayyub R.M., Rai M.F. (2004) – Mercury intoxication in Grass carp
(Ctenopharyngodon idella), Pakistan veterinary Journal, 24(1), 33-38
Mela M., Randi M.A.F., Ventura D.F., Carvalho CEV, Pelletier E.,
Oliviera Riberio C.A. (2007) – Effects of dietary methilmercury on liver and
kidney histology in the neotropical fish Hoplias malabaricus, Ecotoxicol Environ
Saf., Feb.10: 17296226 (P, S, E, B, D)
Veena B. Radhakrishnan C.K., Chacko J. (1997) - Heavy metal induced
biochemical effects in an estuarine teleost, Indian J. Marine Sci, 26:74-78.
