THE USE OF THE ANTI-VENOM SPECIFIC ANTIBODIES ISOLATED FROM DUCK EGGS FOR INACTIVATION OF THE VIPER VENOM
Keywords:
viper venom, antibodies, duck eggs, protection testAbstract
The activity of specific anti-venom can be demonstrated using protection test in
laboratory mice. Our study aimed to emphasize the possibility of viper venom
inactivation by the antibodies produced and isolated from duck eggs and also to the
activation concentration of these antibodies. The venom used for inoculation was
harvested from two viper species (Vipera ammodytes and Vipera berus). The
immunoglobulin extract had a better activity on the venom from Vipera berus
compared to the venom from Vipera ammodytes. This could be the result of a better
immunological response, as consequence of the immunization with this type of
venom, compared to the response recorded when the Vipera ammodytes venom was
used. Besides the advantages of low cost, high productivity and reduced risk of
anaphylactic shock, the duck eggs also have high activity up to dilutions of 1/16,
1/32, respectively, with specific activity and 100 surviving in individuals which
received 3 x DL50.
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