The Hypoglicemic Effect of Momordica Charantia Linn in Normal and Alloxan Induced Diabetic Rabbits

Authors

  • Horia Sărăndan USAMVB Timisoara, Calea Aradului 119, Timisoara, Romania
  • Dorica Botău USAMVB Timisoara, Calea Aradului 119, Timisoara, Romania
  • Iosif Ianculov USAMVB Timisoara, Calea Aradului 119, Timisoara, Romania
  • Florina Radu USAMVB Timisoara, Calea Aradului 119, Timisoara, Romania
  • Olga Rada USAMVB Timisoara, Calea Aradului 119, Timisoara, Romania
  • Doru Morar USAMVB Timisoara, Calea Aradului 119, Timisoara, Romania
  • Mihai Sărăndan USAMVB Timisoara, Calea Aradului 119, Timisoara, Romania
  • Maria Șerb USAMVB Timisoara, Calea Aradului 119, Timisoara, Romania
  • Adela Anghel USAMVB Timisoara, Calea Aradului 119, Timisoara, Romania

Keywords:

alloxan, diabetes, glycemia, Momordica, rabbit

Abstract

The present experiment was intended to test the hypoglycemiant effect of an alcoholic extract of roots or of the fruit seeds from “in vitro” regenerated Momordica charantia Linn. plants grown at USAMVB Timisoara. Diabetes was induced to domestic rabbits by administrating alloxan in dose of 80 mg/ kg body weight.
In diabetic rabbits the glycemia decreased by 15.93% ten hours after the administration of the alcoholic extract in dose of 2 ml/kg body weight; the seeds of Momordica charantia Linn. reduced glycemia by 27.42% when administered in dose of 1.5 g/kg body weight. In alloxan recuperated rabbits, 5 hours after administration of the seeds, glycemia dropped 19.26%.
The “in vitro” regenerated plants of Momordica charantia Linn. keep their hypoglycemiant effects.

References

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Published

2023-10-03