Alteration of some Biochemical and Haematological Parameters in the Dairy Cows Due to the Intake of Mycotoxin Contaminated Feeds

Authors

  • Violeta Elena Simion Faculty of Veterinary Medicine, Spiru Haret University, Masina de Paine Street, No.47, Bucharest, 774275, Romania
  • Gheorghe Pârvu Faculty of Veterinary Medicine, Spiru Haret University, Masina de Paine Street, No.47, Bucharest, 774275, Romania
  • Elena Potecea Faculty of Veterinary Medicine, Spiru Haret University, Masina de Paine Street, No.47, Bucharest, 774275, Romania
  • Luiza Bădic Faculty of Veterinary Medicine, Spiru Haret University, Masina de Paine Street, No.47, Bucharest, 774275, Romania
  • Monica Pârvu Faculty of Veterinary Medicine, Spiru Haret University, Masina de Paine Street, No.47, Bucharest, 774275, Romania

Keywords:

biochemical parameters, dairy cows, feed, mycotoxins

Abstract

The hepatogenic role of mycotoxins is well-known, but their action on some biochemical and haematological parameters in the dairy cows is yet to be completely clarified. The investigation monitored the modification of blood test values and of some biochemical parameters from the serum and urine of dairy cows reared in small family farms and which consumed feeds contaminated with mycotoxins.
Ten blood samples and 10 urine samples were collected and subsequently analysed. The samples were collected from 5 family farms, one in each of the following countied: Dolj, Giurgiu. Ilfov, Călăraşi and Galaţi.
The blood and urine samples were analysed for their biochemical parameters.
The results of the biochemical analyses of the blood and urine samples were correlated with the results of the mycotoxicological analysis of 105 samples of forages collected from the surveyed family dairy farms.
The results showed that some biochemical parameters exceeded the normal physiological level, which may be the result of a defence reaction of the organism to the aggressive action of the mycotoxins identified in the forages given to the dairy cows.

References

Atroshi F., A. Rizzo, I. Biese, P. Veijalainen, H. Saloniemi, S. Sankari, K. Anderson, Fumonisin B1-induced DNA damage in rat liver and spleen: effects of pretreatment with coenzyme O10, L-carnitine, atocopherol and selenium, Pharmacol. Res., 1999, 40:459-67.

Atroshi F., A. Rizzo, S. Sankari, I. Biese, T. Westermarch, P. Veijalainen, Liver enzyme activities of rats exposed to ochratoxin A and T-2 toxin with antioxidants, Bull Environ. Contamin. Toxicol., 2000, 64:586-92.

Buonaccorsi A., G. Croce, G. Della, M. Bizzeti, G. Guidi, Esplorazione funzionale del fegato di bovine alimentate conmais insilato a contenuto sub-tossico di aflatossina, Ann., Fac. Med. Vet. Pisa, 1981, 34:271-77.

Helferich W.G., R.L. Baldwin, D.P. Hsieh, 14C-aflatoxin B1 metabolism in lactating goats and rats, J. Anim. Sci., 1986, 62:697-705.

Kelly V.P., E.M. Ellis, M.M. Manson, S.A. Chanas, G.J. Moffat, R. McLeod, D.J. Judah, G.E. Neal, J.D. Hayes, Chemoprevention of aflatoxin B1 hepatocarcinogenesis by coumarin, a natural benzopyrone that is a potent inducer of aflatoxin B1-aldehyde reductase, the glutathione S-transferase A5 and P1 subunits and NAD(P)H:quinine oxidoreductase in rat liver, Canc. Res., 2000, 60:957-69.

Lynch G.P., F.T. Covey, D.F. Smith, B.T. Weinland, Response of calves to a single dose of aflatoxin, J. Anim. Sci., 1972, 35:65-8.

Ray A.C., B. Abbitt, S.R. Cotter, M.J. Murphy, J.C. Reagor, R.M. Robinson, J.E. West, H.W. Whitford, Bovine abortion and death associated with consumption of aflatoxin-contaminated peanuts, J. Am. Vet. Med. Assoc., 1986, 188:1187-88.

Pârvu Ghe., Supravegherea nutriţional metabolică a animalelor, Editura Ceres, Bucureşti, 1992.

Ghergariu S., A. Pop, L. Kadar, Marina Spînu, 2000, Manual de laborator clinic veterinar, Edit. All, 2000, ISBN 973-684-112-X.

Applebaum R.S., E.H. Marth, Responses of dairy cows to dietary aflatoxin: concentration of blood serum constituents and hormones associated with liver-kidney dysfunction and maintenance of lactation, Europ. J. Appl. Microbiol. Biotechnol., 1983, 18:381-386.

Lynch G.P., G.C. Todd, W.T. Shalkop, L.A. Moore, Responses of dairy calves to aflatoxin-contaminated feed, Journal of Dairy Science, 1970, Vol. 53, No.1, 63-71.

Seeling K., Lebzien P., Dänicke S., Spilke J., Südekum K.H., Flachowsky G., Effects of level of feed intake and Fusarium toxin-contaminated wheat on rumen fermentation as well as on blood and milk parameters in cow, J. Anim. Physiol. Anim. Nutr. (Berl), 2006, 90(3-4) :103-115.

Côté, L.M., A.M. Dahlem, T. Yoshizama and W.B. Buck., Excretion of deoxynivalenol and its metabolite in milk, urine and feces of lactating dairy cows. J. Dairy Sci., 1986, 69:2416-23

Schuh M., Klinische Auswirkungen der in Őesterreich vorkommenden Mykotoxine. Wien. Tierärztl. Monatschr.,1981, 68, pp.308-12.

Buening G.M., Mann D.D., Hook B., Osweiler G.D., The effect of T-2 toxin on the bovine immune system: cellular factors, Vet. Immunol. Immunopathol.,1982, 3(4):411-417

Agag B.I., Mycotoxins in food and feeds. 5-Tricothecenes. A-T-2 Toxin, Ass. Univ. Bull. Environ. Res., 2005, Vol. 8 No.2, , pg. 107, 109-110, 113-114.

Sharma R.P., Immunotoxicity of mycotoxins, J. Dairy Sci., 1993, 76(3):892-897.

Ghergariu S., Bazele patologiei medicale a animalelor, Edit. All, Vol. 1, 1994, pp. 283-299.

Downloads

Published

2023-10-03