SISTER CHROMATID EXCHANGES IN RIVER BUFFALO FEMALES WITH CHROMOSOMAL FRAGILITY
Keywords:
buffaloes, chromosomes, sister chromatid exchangesAbstract
Sister chromatid exchange (SCE) technique is considered a very important test to
check potential damage to the DNA, expressed by chromosomal fragility and
associated with high rates of SCEs. In the present study we report the preliminary
results of our investigation on chromosomal fragility identified in buffalo
chromosomes and the relationship with the increased SCE levels. The karyotype
analyses carried out on a group of 16 river buffalo females selected and treated for
hormonal stimulation and on a control group of 16 normal river buffalo females
revealed that three of the treated females were found to carry a higher number of
breakages/cell comparative with the control group. The mean number of SCE/cell in
the three treated females was higher (X=11.8) than that of those observed in the
control group (X=7.8).
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