Potassium Dichromate (Cr VI) Impact on Fundamental Biomarkers of Reproductive Functionality in Female Rats (Six Months Exposure)

Alexandra Trif, Snejana Petrovici, Violeta Igna, Simona Steliac, Milca Petrovici

Abstract


The study carried out on 28 white Wistar adult female rats, divided in four groups: one control and three experimental, exposed in drinking water for six months to 25 ppm Cr VI – LOAEL (E1), 50 ppm Cr VI - 2XLOAEL (E2), 75 ppm CR VI - 3XLOAEL (E3), pointed out: significant (p<0.01) increase of sexual cycle duration comparative to control group and over the physiological limits, in direct correlation to exposure level; modification of sexual stages regularity: significant decrease of sexual cycles percentage with proestrus, estrus and diestrus in physiological limits as duration comparative to control group and inversely correlated to exposure level; appearance of sexual cycles with absent proestrus and estrus directly correlated to exposure level and of prolonged diestrus, directly, significantly (p<0.01) correlated to exposure level.


Keywords


female; hexavalent chromium; rat; sexual cycle

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LUCRARI STIINTIFICE ZOOTEHNIE SI BIOTEHNOLOGII (SCIENTIFIC PAPERS ANIMAL SCIENCE AND BIOTECHNOLOGIES)

ISSN print 1841 - 9364
ISSN online 2344 - 4576
ISSN-L  1841 - 9364
(former ISSN 1221-5287, E-ISSN 1841-9364)

PUBLISHER: AGROPRINT Timisoara, Romania
PAPER ACCESS: Full text articles available for free
FREQUENCY: Semiannual
PUBLICATION LANGUAGE: English
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Banat´s University of Agricultural Sciences and Veterinary Medicine "King Michael I of Romania" from Timisoara
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