Potassium Dichromate Impact on some Biomarkers of Female Reproductive System Performances (Litter Size, Sex Ratio) and Physical Development (Vaginal Opening) in Rats (F2 Generation)

Snejana Petrovici, Alexandra Trif, Eugenia Dumitrescu, Florin Muselin, Milca Petrovici

Abstract


The aim of this study was to emphasize potassium dichromate impact on some female reproductive system performances and physical development biomarkers in rats. Exposure to potassium dichromate (25 - LOAEL, 50 and 75 ppm Cr VI) in utero, during suckling period and until sexual maturity, of F2 female white Wistar rats generation (derived from F0 and F1 generations, exposed to the same Cr VI levels), pointed out significant decrease of alive/increase of dead pup number at birth, impaired sex ratio in male favor, significant dose dependent delay of puberty onset and lower body weight comparative to the optimum one at sexual maturity - the vaginal opening moment.


Keywords


rat; female; sex ratio; vaginal opening

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Scientific Papers Animal Science and Biotechnologies publish open access articles under the terms of the Creative Commons Attribution 4.0 Licence (read full legal code).


LUCRARI STIINTIFICE ZOOTEHNIE SI BIOTEHNOLOGII (SCIENTIFIC PAPERS ANIMAL SCIENCE AND BIOTECHNOLOGIES)

ISSN print 1841 - 9364
ISSN online 2344 - 4576
ISSN-L  1841 - 9364
(former ISSN 1221-5287, E-ISSN 1841-9364)

PUBLISHER: AGROPRINT Timisoara, Romania
PAPER ACCESS: Full text articles available for free
FREQUENCY: Semiannual
PUBLICATION LANGUAGE: English
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Banat´s University of Agricultural Sciences and Veterinary Medicine "King Michael I of Romania" from Timisoara
Faculty of Animal Science and Biotechnologies
300645, Timişoara, Calea Aradului 119, Romania

E-mail: spasb [at] animalsci-tm.ro
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