Quantitative Analysis of the Rat Testes after an Acute Cadmium and Diazinon Administration

Robert Toman, Mária Adamkovičová, Svätoslav Hluchý, Michal Cabaj, Jozef Golian

Abstract


Changes in the rat testes caused by cadmium and organophosphate insecticide diazinon were evaluated using the morphometry methods. 36 hours after an single intraperitoneal administration of cadmium at a dose of 2 mg/kg b.w., diazinon 20 mg/kg b.w., and cadmium-diazinon 2 and 20 mg/kg, respectively, a significant increase in dilatation of blood vessels (P<0.05) after an administration of diazinon, significant increase of intraepithelial spaces volume in testes in cadmium exposed group (P<0.05) and highly significant increase in intraepithelial spaces volume in cadmium-diazinon treated animals (P<0.0001) were observed. Cadmium and diazinon are toxic for male reproduction and can pose a higher reproductive effects when mixture of both toxicants enters the body.


Keywords


cadmium; diazinon; morphometry; rat; testis

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Scientific Papers Animal Science and Biotechnologies publish open access articles under the terms of the Creative Commons Attribution 4.0 Licence (read full legal code).


LUCRARI STIINTIFICE ZOOTEHNIE SI BIOTEHNOLOGII (SCIENTIFIC PAPERS ANIMAL SCIENCE AND BIOTECHNOLOGIES)

ISSN print 1841 - 9364
ISSN online 2344 - 4576
ISSN-L  1841 - 9364
(former ISSN 1221-5287, E-ISSN 1841-9364)

PUBLISHER: AGROPRINT Timisoara, Romania
PAPER ACCESS: Full text articles available for free
FREQUENCY: Semiannual
PUBLICATION LANGUAGE: English
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Banat´s University of Agricultural Sciences and Veterinary Medicine "King Michael I of Romania" from Timisoara
Faculty of Animal Science and Biotechnologies
300645, Timişoara, Calea Aradului 119, Romania

E-mail: spasb [at] animalsci-tm.ro
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