The effect of gemmoderivatives on probiotic and pathogenic microorganisms

LAURA DORINA Dinu, Cristina Popescu, Alexandra Atitieni


Gemmotherapy is a biotherapeutical treatment method that uses extracts from fresh meristematic tissues obtained from different parts of the plants like buds, young twigs, seeds, seedlings, bark of young branches or rootlets. The gemmoderivatives composition is complex, containing a higher amount of active ingredients that can no longer be found in the adult plant. Therefore, the object of the study was to investigate the effects of commercial meristematic extracts from buds of Ginkgo biloba, young branches of blueberry (Vaccinium myrtillus), cranberry (Vaccinium vitis-idaea) and heather (Calluna vulgaris) on bacteria from 2 probiotics (Linex Forte, Eubiotic) and pathogenic Staphylococcus aureus and Escherichia coli and on two fungal strains isolates from dogs with mycotic infections. The antimicrobial effect was investigated using disc diffusion method and the inhibition zones were compared with that of different standards like ampicillin for antibacterial activity and nystatin for antifungal activity. Also, the microbial growth in culture media supplemented with tested gemmoderivatives were spectrophotometric analysed. The heather gemmoderivatives showed prominent antifungal activity while E. coli and S. aureus growth was inhibited mainly by Ginkgo biloba extract. The study revealed that gemmoderivatives have different inhibition patterns on probiotic strains and blueberry meristematic extract slightly increased the growth of probiotic strains. This preliminary research is the first report on the effect of gemmoderivatives on commercial probiotics.   



gemmoderivatives, probiotic, pathogenic bacteria and fungi

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