THE IMPACT OF IN VIVO ADMINISTRATION OF A SYNTHESIS PRODUCT (BY-PRODUCT OF SALICYLIC ACID) ON SOME BIOCHEMICAL PARAMETERS ON RATS

LETITIA STANA, ALEXANDRA TRIF, F. MUSELIN, ALFA XENIA LUPEA, MIRABELA PADURE

Abstract


The goal of this study is to establish the in vivo impact of a by-product of salicylic acid, 5-cloro-2-hidroxy-azotyl-sulfamoil-phenyl benzamyde synthesis product (5ClSA-SA), synthesized at the Technical University, Faculty of Industrial Chemistry of Timisoara, on some parameters of energetic metabolism. The experimental results shows that the synthesis product has induced a strong significant increase (p<0.01) of glycemia compared to tests, in direct relation with administration period and a fluctuation of cholesterol values with decrease followed by strong significant increase (p<0.01) compared to tests. Glycemia and plasmatic cholesterol values were situated between physiological limits. Triglycerides registered strong significant increases (p<0.01) in direct relation with administration period, over the physiological limits.


Keywords


glycemia; cholesterol; triglyceride; rat

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LUCRARI STIINTIFICE ZOOTEHNIE SI BIOTEHNOLOGII (SCIENTIFIC PAPERS ANIMAL SCIENCE AND BIOTECHNOLOGIES)

ISSN print 1841 - 9364
ISSN online 2344 - 4576
ISSN-L  1841 - 9364
(former ISSN 1221-5287, E-ISSN 1841-9364)

PUBLISHER: AGROPRINT Timisoara, Romania
PAPER ACCESS: Full text articles available for free
FREQUENCY: Semiannual
PUBLICATION LANGUAGE: English
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Banat´s University of Agricultural Sciences and Veterinary Medicine "King Michael I of Romania" from Timisoara
Faculty of Animal Science and Biotechnologies
300645, Timişoara, Calea Aradului 119, Romania

E-mail: spasb [at] animalsci-tm.ro
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