THE INFLUENCE OF POTASSIUM DICHROMATE Cr (VI) ADMINISTRATION DURATION ON GLOBULAR RESISTANCE IN FEMALE RATS

LETIŢIA STANA, ALEXANDRA TRIF, SNEJANA PETROVICI, LOREDANA GABRIELA STANA, CORINA GRĂVILĂ

Abstract


The „in vivo” experiment has had as aim the study of different Cr(VI) doses administration on globular resistance in female rats related to administration duration. Study was carried out on 56 female rats divided in 8 groups, 6 experimental and 2 control that received potassium dichromate in drinking water in doses of 25 ppm, 50 ppm and 75ppm Cr(VI), for 3 months, respectively, 6 months. Decrease of globular resistance (in terms of haemolysis degree in hypotonic solutions) at increasing dose (up to 0.8% NaCl at 75 ppm dose) in all experimental groups, in direct relation with the duration of administration was registered. Control groups were in physiological limits. The results of the present study revealed the affecting of erythrocyte membrane in function of administration duration and chromium intake level, because of oxidative lesions produced by it.


Keywords


chromium dichromate; rats; globular resistance

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LUCRARI STIINTIFICE ZOOTEHNIE SI BIOTEHNOLOGII (SCIENTIFIC PAPERS ANIMAL SCIENCE AND BIOTECHNOLOGIES)

ISSN print 1841 - 9364
ISSN online 2344 - 4576
ISSN-L  1841 - 9364
(former ISSN 1221-5287, E-ISSN 1841-9364)

PUBLISHER: AGROPRINT Timisoara, Romania
PAPER ACCESS: Full text articles available for free
FREQUENCY: Semiannual
PUBLICATION LANGUAGE: English
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Banat´s University of Agricultural Sciences and Veterinary Medicine "King Michael I of Romania" from Timisoara
Bioengineering Faculty of Animal Resources
300645, Timişoara, Calea Aradului 119, Romania

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